Nickel sensitization is a human health concern due to its marked prevalence in the general population.  However, the risk of becoming nickel-sensitized or having a nickel ACD reaction (if already nickel-sensitized) can be managed and minimized through reduced exposure to nickel-releasing items.  In the workplace, exposure reduction includes personal protective equipment and other risk management measures.  For consumers, exposure can be reduced through restriction of direct and prolonged exposure to items releasing nickel in amounts greater than the threshold for nickel ACD.